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Index > Protein center > FBLN5(Gene name) > Human
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  • FBLN5 (Gene name),
  • Fibulin-5 (Protein name ),  FBLN5_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    FBLN5(UNQ184/PRO210;DANCE);
    Protein name:
    Fibulin-5(FIBL-5);
    Alternative:
    Urine p50 protein(UP50);Developmental arteries and neural crest EGF-like protein(Dance);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Could be a vascular ligand for integrin receptors and may play a role in vascular development and remodeling.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    448
    Sequence:
    50:
    MPGIKRILTV | TILALCLPSP | GNAQAQCTNG | FDLDRQSGQC | LDIDECRTIP | 
    100:
    EACRGDMMCV | NQNGGYLCIP | RTNPVYRGPY | SNPYSTPYSG | PYPAAAPPLS | 
    150:
    APNYPTISRP | LICRFGYQMD | ESNQCVDVDE | CATDSHQCNP | TQICINTEGG | 
    200:
    YTCSCTDGYW | LLEGQCLDID | ECRYGYCQQL | CANVPGSYSC | TCNPGFTLNE | 
    250:
    DGRSCQDVNE | CATENPCVQT | CVNTYGSFIC | RCDPGYELEE | DGVHCSDMDE | 
    300:
    CSFSEFLCQH | ECVNQPGTYF | CSCPPGYILL | DDNRSCQDIN | ECEHRNHTCN | 
    350:
    LQQTCYNLQG | GFKCIDPIRC | EEPYLRISDN | RCMCPAENPG | CRDQPFTILY | 
    400:
    RDMDVVSGRS | VPADIFQMQA | TTRYPGAYYI | FQIKSGNEGR | EFYMRQTGPI | 
    448:
    SATLVMTRPI | KGPREIQLDL | EMITVNTVIN | FRGSSVIRLR | IYVSQYPF
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    Pfam:
    MIM:
    Pfam:
    SMR:
    KEGG:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human FIBL-5
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    E0209h
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    96T
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    ELISA Kit for Human FIBL-5
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    E0209m
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    ELISA Kit for Human FIBL-5
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    E0209b
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    96T
    ELISA Kit for Human FIBL-5
    Cat.:
    E0209r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human FIBL-5
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    U0209m
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    Packing:
    96T
    CLIA Kit for Human FIBL-5
    Cat.:
    U0209b
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human FIBL-5
    Cat.:
    U0209h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human FIBL-5
    Cat.:
    U0209r
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human FIBL-5
    Polyclonal Antibody for Human FIBL-5
    Cat.:
    P0209Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human FIBL-5
    Cat.:
    P0209Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human FIBL-5
    Cat.:
    P0209Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human FIBL-5
    Monoclonal Antibody for Human FIBL-5
    Monoclonal Antibody for Human FIBL-5
    Monoclonal Antibody for Human FIBL-5
    Protein for Human FIBL-5
    Protein for Human FIBL-5
    Protein for Human FIBL-5
    Protein for Human FIBL-5

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    References
    1. 1.
      Kostka G.
      Submitted (1999-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Melanoma.
    2. 2.
      "DANCE, a novel secreted RGD protein expressed in developing, atherosclerotic, and balloon-injured arteries."
      Nakamura T. , Ruiz-Lozano P. , Lindner V. , Yabe D. , Taniwaki M. , Furukawa Y. , Kobuke K. , Tashiro K. , Lu Z. , Andon N.L. , Schaub R. , Matsumori A. , Sasayama S. , Chien K.R. , Honjo T.
      J. Biol. Chem.274:22476-22483(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      Zemel R. , Sholto O. , Shaul Y.
      Submitted (1998-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Urine.
    4. 4.
      "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
      Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
      Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    5. 5.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
      Submitted (2004-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    6. 6.
      "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries."
      Otsuki T. , Ota T. , Nishikawa T. , Hayashi K. , Suzuki Y. , Yamamoto J. , Wakamatsu A. , Kimura K. , Sakamoto K. , Hatano N. , Kawai Y. , Ishii S. , Saito K. , Kojima S. , Sugiyama T. , Ono T. , Okano K. , Yoshikawa Y. , more...
      DNA Res.12:117-126(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Placenta.
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Lung.
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT
    10. 10.
      "Homozygosity for a missense mutation in fibulin-5 (FBLN5) results in a severe form of cutis laxa."
      Loeys B. , van Maldergem L. , Mortier G. , Coucke P. , Gerniers S. , Naeyaert J.-M. , de Paepe A.
      Hum. Mol. Genet.11:2113-2118(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT ARCL1A PRO-227
    11. 11.
      "Genetic heterogeneity of cutis laxa: a heterozygous tandem duplication within the fibulin-5 (FBLN5) gene."
      Markova D. , Zou Y. , Ringpfeil F. , Sasaki T. , Kostka G. , Timpl R. , Uitto J. , Chu M.-L.
      Am. J. Hum. Genet.72:998-1004(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN ADCL2
    12. 12.
      "Missense variations in the fibulin 5 gene and age-related macular degeneration."
      Stone E.M. , Braun T.A. , Russell S.R. , Kuehn M.H. , Lotery A.J. , Moore P.A. , Eastman C.G. , Casavant T.L. , Sheffield V.C.
      N. Engl. J. Med.351:346-353(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ARMD3 LEU-60; GLN-71; SER-87; THR-169; TRP-351; THR-363 AND GLU-412
    13. 13.
      "Homozygous missense mutation in fibulin-5 in an Iranian autosomal recessive cutis laxa pedigree and associated haplotype."
      Elahi E. , Kalhor R. , Banihosseini S.S. , Torabi N. , Pour-Jafari H. , Houshmand M. , Amini S.S.H. , Ramezani A. , Loeys B.
      J. Invest. Dermatol.126:1506-1509(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT ARCL1A PRO-227
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